회사소개

고통 받는 사람들에게 편안함을, 원하는 사람들에게는 만족을,
희망을 잃어버린 사람들에게는 기회를 만들어주는 기업! 휴림바이오셀입니다.

R&D센터

휴림바이오셀의 기업부설연구소로서, 2006년부터 성체줄기세포 전문연구기관으로 운영되고 있습니다.
성체줄기세포에 대한 폭넓은 연구를 통해 세포의 성격과 특징을 구분하고 이를 바탕으로 치료제 개발에 매진하고 있습니다.
또한 줄기세포를 활용하기 위한 기술 개발에 주력하고 기술 상용화에 주력함으로써,
성체줄기세포를 이용한 난치성 질환의 치료에 이바지 하고자 합니다.

성체줄기세포의 체내외 시험 및 자원화를 위해 R&D센터 는 4개의 연구팀으로 구성되어있습니다
R&D1팀
R&D 1팀

줄기세포의 분리, 배양, 분화 특성
분석 및 비교 시험

R&D 2팀

줄기세포의 냉동보존을 통한
미래 자원화 기술 개발

R&D2팀
R&D3팀
R&D 3팀

개발중인 세포치료제의 비임상시험 분석 및
다기관협력 연구

휴림바이오셀 R&D센터의 장점

01

다양한 인체 조직으로부터
줄기세포의 확보 및
세포주 다량 보유

02

세포에 따른
차별적 공정 도입에 따른
정확한 제조 및 관리

03

냉동보존에 대한
지속적인 개발을 통한
최고의 세포 보관 기술

04

질환별 의료연구팀과의
공동연구를 통한
전문적 치료제 개발

국내/해외 특허
국내 등록 특허
10-0683198 신경전구세포를 도파민성 신경세포로 분화시키는 방법 및 그에 사용되는 배지
10-0683199 신경전구세포를 콜린성 신경세포로 분화시키는 방법 및 그에 사용되는 배지
10-0779499 정밀 피펫
10-0801963 액체 샘플의 흡입/배출량이 디스플레이되는 피펫
10-0803576 지방줄기세포 및 지방세포를 포함한 이식용 조성물
10-0883581 안면피하 지방조직 또는 탯줄조직 유래 성체 줄기세포를 이용한 간세포 분화방법 및 그에 사용되는 간세포 분화배양액
10-0895324 성체줄기세포를 이용한 인슐린분비세포로의 분화유도방법
10-0956267 엘라스틴을 안정화제로서 함유하는 반유동성 이식용 조성물
10-0800400 인간 줄기세포주 분화에 관련된 유전자
10-0807618 인간줄기세포주분화측정용마이크로어레이키트
10-1137964 지방 조직 이식용 주사기 및 이를 갖는 지방 조직 분배 장치
10-1316573 재생성 세포 추출유닛 및 재생성 세포 추출시스템
10-1269906 재생성 세포 추출유닛 및 재생성 세포 추출시스템 (12번 특허 분할특허)
10-1316574 멀티웨이 밸브 및 이를 이용한 재생성 세포 추출시스템
10-1263820 재생성 세포 추출장치
10-1263821 멀티웨이 밸브 및 이를 이용한 재생성 세포 추출시스템
10-1251217 중간엽 줄기세포의 내배엽성 세포로의 교차분화 방법
10-1121154 지방줄기세포 또는 지방세포를 포함한 이식용 조성물
10-1316575 페리스테틱 펌프 및 이를 이용한 재생성 세포추출 시스템
10-1144151 모낭 줄기세포로부터 멜라닌 줄기세포의 분리방법
10-1266943 멜라닌 세포의 수를 증가시키는 방법
10-1315204 튜브용밸브
10-1357160 재생성 세포 추출 시스템 및 이를 이용한 재생성 세포 추출 방법
10-1466923 재생성 세포 추출 장치, 재생성 세포추출시스템, 이를 이용한 세포 추출방법
10-1679671 재생성 세포 추출시스템
10-2024740 간엽줄기세포의 냉동보존용 배지 및 이를 이용한 간엽줄기세포의 냉동보존방법
10-2024742 조혈줄기세포의 냉동보존용 배지 및 이를 이용한 조혈줄기세포의 냉동보존방법
국내 출원 특허
10-2012-0040731 제대-유래의 간엽줄기세포 생산방법
10-2015-0707815 백반증 치료용 약학제재
10-2016-0045633 재생성 세포 추출 시스템
해외 등록 특허
싱가폴-158192 지방줄기세포 또는 지방세포를 포함한 이식용 조성물
중국-ZL 20108005953.6 재생성세포추출유닛 및 재생성 세포 추출시스템
일본-5923466 재생성세포추출유닛 및 재생성 세포 추출시스템
미국-9,388,377 재생성세포추출유닛 및 재생성 세포 추출시스템
중국-ZL 201480016369.X 재생성세포 추출 장치, 재생성 세포추출시스템, 이를 이용한 재생성 세포 추출방법
태국-1201001975 재생성 세포 추출유닛 및 재생성 세포 추출시스템
학술성과
줄기세포 분리 확립 분야
The 5th Biannual Meeting of Pacific Rim Society for Fertility and Sterility Human adipose tissue-derived stem cells have characteristics of multipotent stem cells
The 5th Biannual Meeting of Pacific Rim Society for Fertility and Sterility Human cord serum as a fetal bovine serum substitute for the culture of human amnion-derived stem cells
The 23rd Annual Meeting of Korean Society of Developmental Biology Preliminary study of human adipose tissue-derived stem cells (ADSCs): Characterization of ADSCs according to an age bracket of consent volunteers
The 5th International Federation of Adipose Therapeutic and Science Patterns of gene expression related to the stemness and senescence in long-termed adipose-derived stem cells
The 9th International Society for Stem Cell Research Comparison of expansion and differentiation ability of mesenchymal stem cells from the different tissue sources
The 17th International Society for Cell Therapy Proliferation and characterization of human umbilical cord derived stromal progenitor cells under culture condition
2010 KSBMB annual meeting Evaluation of isolation and proliferation methods for stem cells from human umbilical cord
The 9th International Society for Stem Cell Research Comparative analysis of gene expression and fibroblast colony-forming abilities of human adipose- or umbilical cord-derived progenitor cells
The 23rd Annual Meeting of the Korean Society for Molecular and Cellular Biology Differential gene expression depending on cultivation period of umbilical cord-derived mesenchymal stem cells
The 3rd International Conference of Society of Biological Engineering Preparation of homogeneous progenitor population from human umbilical cord tissue using gene expression profiling
2013 KSBB annual meeting Characterization of umbilical cord derived mesenchymal stem cells (hUC-MSCs) depending on their isolation methods
The 11th International Society for Stem Cell Research Gene expression profiling of human umbilical cord derived mesenchymal stem cells depending on passage under modified MSC culture medium
줄기세포 배양 분화 분야
The 12th Annual Meeting, International Stem Cell Therapy Differentiation abilities of stem like cells derived from human fat tissues is not dependent on the time of cryopreservation
2006 KSBB Spring Meeting Effects of serum sources on differentiation abilities in adult stem cells
The 5th Biannual Meeting of Pacific Rim Society for Fertility and Sterility In vitro differentiation of human adipose tissue-derived stem cells into hepatocyte-like cells
The 5th Biannual Meeting of Pacific Rim Society for Fertility and Sterility In vitro differentiation of human adipose tissue-derived stem cells into insulin producing cells
The 4th Annual Meeting International Fat Applied Technology Society Consideration of the conventional lineage specific markers for differentiation potential of human adipose tissue-derived stem cells
The 14th International Society for Cell Therapy Consideration point for differentiation of human adipose tissue-derived stem cells into mature adipocytes
The 5th International Federation of Adipose Therapeutic and Science The characterization of islets formed during adipocyte differentiation of human adipose tissue-derived stem cells
The 7th International Federation of Adipose Therapeutic and Science Differential induction for in vitro adipogenesis bioassay using human adipose-derived stem cells
The 7th International Federation of Adipose Therapeutic and Science Comparison of osteogenesis ability in vitro between adipose-derived stem cells and progenitor cells isolated from bone-related tissues
The 17th International Society for Cell Therapy Enhancement of myogenic differentiation of human adipose tissue derived stromal cells in vitro
줄기세포 은행 보관 분야
2006 KSBB Spring Meeting Evaluation of modified processing and cryopreservation method in umbilical cord blood derived nucleated cells
The 44th Annual Meeting of the Society for Cryobiology A preliminary study for cryopreservation components in survival and proliferation of human adipose derived stem cells
The 16th International Society for Cell Therapy The effect of antifreeze proteins on adipose derived stem cells during cryopreservation
2010 KSBMB annual meeting A preliminary study for optimal storage of human dental pulp derived mesenchymal stem cells
2011 KSBB Fall Meeting Study of the substitution for xenogenic component in the cryopreservation solution of human adipose-derived progenitor cells
2011 Cellular Programs and Reprogra -mming Cold Spring Harbor Asia Meeting Preliminary study to develop the cryopreservation methods for safe application of adipose derived stem cells
The 3rd International Conference of Society of Biological Engineering Characterization of thawed human hematopoietic and/or mesenchymal stem cells using colony forming unit assay
The 11th International Society for Stem Cell Research Beneficial Effect of pan-caspase inhibitor for Cryopreservation of Human Umbilical Cord Derived Mesenchymal Stem Cells (hUC-MSCs)
The 32th Annual Meeting of Korean Society of Developmental Biology Improved conditions for cryopreservation of human adipose tissue or umbilical cord derived mesenchymal stem cells
The 16th Annual Meeting American society of gene and cell therapy Culture and cryopreservation of human epidermal melanocytes (MC) for preclinical trials
줄기세포 재생 효력 분야 Ⅰ
The 5th International Society for Stem Cell Research Regeneration potential of human adipose tissue-derived stem cells on cryo-induced injury of mouse thigh muscle
The 6th International Society for Stem Cell Research Evaluation for cardiomyogenic regeneration of human CD34-positive adipose-derived stromal progenitor cells
The 16th International Society for Cell Therapy Development for preclinical trial of human skin melanocyte progenitor cells
The 2nd TERMIS World Congress Morphological study on the transplantation of human adipose-derived stem cells in a rabbit model of traumatic degeneration of lumbar disc
The 28th Annual Meeting of Korean Society of Developmental Biology Therapeutic approach to the neurodegenerative diseases based on stem cell bank
The 17th International Society for Cell Therapy A comparative study of effect of the oxygen microenvironment on in vitro the angiogenesis of human adipose tissue- or umbilical cord-derived stromal progenitor cells
The 29th Annual Meeting of Korean Society of Developmental Biology Neuroprotective properties and neural differentiation of the human adipose tissue-derived mesenchymal stem cells transplanted in ischemic rat brain injury
The 29th Annual Meeting of Korean Society of Developmental Biology Potential applications of human adipose derived stem cells
The 16th World Congress on In Vitro Fertilization Improved conditions for cryopreservation of human adipose tissue or umbilical cord derived mesenchymal stem cells
The 32th Annual Meeting of Korean Society of Developmental Biology Mesenchymal stem cells from aspirated adipose tissue can assist in ex vivo expansion of melanocytes for cell therapy
The 32th Annual Meeting of Korean Society of Developmental Biology Preclinical examination of transplantation of human melanocytes and adipose-derived stromal cells for the treatment of vitiligo
The 16th Annual Meeting American society of gene and cell therapy Qualification for human umbilical cord derived mesenchymal stem cells(hUC-MSCs) for regenerative medicine
줄기세포 재생 효력 분야 Ⅱ
Mol Cells (2006) 21(3);343-355 Profiling of differentially expressed genes in human stem cells by cDNA microarray
Neuroreport (2007) 18(11);35-38 Estrogen simulates the neuronal differentiation of human umbilical cord blood mesenchymal stem cells (CD34-)
Cloning Stem Cells (2007) 9(4);581-594 Ex vivo characteristics of human amniotic membrane-derived stem cells
Dev Reprod (2008) 12(1);31-39 Differentiation of dopaminergic and cholinergic neurons form mesenchymal-like stem cells derived from the adipose tissue
Dev Reprod (2011) 15(2);99-111 Chondrogenesis of human adipose tissue derived mesenchymal stem cells seeded in gelatin-chondroitin-glucosamine scaffold
World Neurosurgery (2012) 78(3); 364-371 Transplantation of human adipose-derived stem cells in a rabbit model of traumatic degeneration of lumbar discs
Aesthetic Plast Surg (2013) 37(4);802-8 Safety of adipose-derived stem cells and collagenase in fat tissue preparation
Mol Cells (2013) 36;534-541 Administration of mesenchymal stem cells and ziprasidone enhanced amelioration of ischemic brain damage in rats
Animal Cell Systems (2013) 17(3);160-169 Combination effect of p-hydroxybenzyl alcohol and mesenchymal stem cells on the recovery of brain damage in a rat model of brain ischemia
Tissue Cell (2014) 46;127-13 Valproic acid promotes differentiation of hepatocyte-like cells from whole human umbilical cord-derived mesenchymal stem cells
Regulatory Toxicology and Pharmacology (2016) 81;437-447 Human umbilical cord-derived mesenchymal stem cells in acute liver injury: Hepatoprotective efficacy, subchronic toxicity, tumorigenicity, and biodistribution
Gastroenterology (2017)152;1174–1186 Milk fat globule-EGF factor 8, secreted by mesenchymal stem cells, protects against liver fibrosis in mice